Věda a výzkum

Kardiocentrum patří mezi nejaktivnější pracoviště v kardiovaskulárním klinickém výzkumu nejen v rámci České republiky, ale i v rámci mezinárodním. Výzkum je zaměřen na zlepšování diagnostiky, léčby a prevence většiny kardiovaskulárních nemocí: ischemické choroby srdeční včetně infarktu myokardu, ischemické cévní mozkové příhody, poruch srdečního rytmu, ischemické choroby dolních končetin, plicní embolie, srdečních vad aj.

V Kardiocentru jsou řešeny četné národní i mezinárodní výzkumné projekty a granty. Pracovníci Kardiocentra jsou aktivní ve výborech lékařských odborných společností a v redakčních radách předních odborných časopisů.

Nejvýznamnější vědecké publikace Kardiocentra:

P. Widimský et al.: Direct Catheter-Based Thrombectomy for Acute Ischemic Stroke: Outcomes of Consecutive Patients Treated in Interventional Cardiology Centers in Close Cooperation With Neurologists. J Am Coll Cardiol 2015; 66: 487-8.

P. Widimský et al. on behalf of the ESC Council on Stroke. The role of cardiologists in stroke prevention and treatment: position paper of the European Society of Cardiology Council on Stroke. Eur Heart J 2018; 39: 1567-1573.

P. Widimský et al. on behalf of the PRAGUE Study Group Investigators. Long-term outcomes of patients with acute myocardial infarction presenting to hospitals without catheterization laboratory and randomized to immediate thrombolysis or interhospital transport for primary percutaneous coronary intervention. Five years' follow-up of the PRAGUE-2 Trial. Eur Heart J 2007; 28: 679-84.

P. Widimský et al. Multicentre randomized trial comparing transport to primary angioplasty vs immediate thrombolysis vs combined strategy for patients with acute myocardial infarction presenting to a community hospital without a catheterization laboratory. The PRAGUE study. Eur Heart J 2000; 21: 823-31.

P. Toušek et al. Comparison of a Bioresorbable, Magnesium-Based Sirolimus-Eluting Stent with a Permanent, Everolimus-Eluting Metallic Stent for Treating Patients with Acute Coronary Syndrome: the PRAGUE-22 Study. Cardiovasc Drugs Ther. 2021 Sep 10. Online ahead of print.

P. Toušek et al. Two-year follow-up after bioresorbable vascular scaffold implantation in STEMI patients - Results from PRAGUE-19 study. Int J Cardiol 2016; 209: 20-1.

P. Toušek et al. Identification of hibernating myocardium with myocardial contrast echocardiography: comparison with late gadolinium-enhanced magnetic resonance. Int J Cardiol 2008; 128: 117-20.
Z. Moťovská, D.L. Bhatt. 12 months of DAPT after acute coronary syndrome still beats 6 months. Lancet 2018; 391: 1240-1242.

Z. Moťovská et al. on behalf of the PRAGUE-18 Study Group. 1-Year Outcomes of Patients Undergoing Primary Angioplasty for Myocardial Infarction Treated With Prasugrel Versus Ticagrelor. J Am Coll Cardiol 2018; 71: 371-381.

Z. Moťovská et al. on behalf of the PRAGUE-18 Study Group. Prasugrel Versus Ticagrelor in Patients With Acute Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention: Multicenter Randomized PRAGUE-18 Study. Circulation. 2016 Nov 22;134(21):1603-1612

P. Osmančík et al. on behalf of the PRAGUE-17 Trial Investigators. 4-Year Outcomes After Left Atrial Appendage Closure Versus Nonwarfarin Oral Anticoagulation for Atrial Fibrillation. J Am Coll Cardiol 2022; 79: 1-14.

P. Osmančík et al. Five-year outcomes in cardiac surgery patients with atrial fibrillation undergoing concomitant surgical ablation versus no ablation. The long-term follow-up of the PRAGUE-12 Study. Heart Rhythm 2019; 16: 1334-1340.

P. Osmančík et al. A comparison of the VASP index between patients with hemodynamically complicated and uncomplicated acute myocardial infarction. Catheter Cardiovasc Interv 2010; 75: 158-66.
V. Kočka et al. Bioresorbable vascular scaffolds in acute ST-segment elevation myocardial infarction: a prospective multicentre study Prague 19. Eur Heart J 2014; 35: 787-94. 

V. Kočka et al. Optimal Fluoroscopic Projections of Coronary Ostia and Bifurcations Defined by Computed Tomographic Coronary Angiography. JACC Cardiovasc Interv 2020; 13: 2560-2570.

K. Čurila et al. Both selective and nonselective His bundle, but not myocardial, pacing preserve ventricular electrical synchrony assessed by ultra-high-frequency ECG. Heart Rhythm 2020; 17: 607-614.
P. Baláž et al. Oncovascular Surgery: The Current Situation and Future Perspectives in Europe. Eur J Vasc Endovasc Surg 2022; 63: 350-351.